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ICD-10-CM Code D68.5
Primary thrombophilia

Non-Billable Code
Non-Billable means the code is not sufficient justification for admission to an acute care hospital when used a principal diagnosis. Use a child code to capture more detail.
| ICD-10 from 2011 - 2016

ICD Code D68.5 is a non-billable code. To code a diagnosis of this type, you must use one of the three child codes of D68.5 that describes the diagnosis 'primary thrombophilia' in more detail.

The ICD code D685 is used to code Protein S deficiency

Protein S deficiency is a disorder associated with increased risk of venous thrombosis. Protein S, a vitamin K-dependent physiological anticoagulant, acts as a nonenzymatic cofactor to activate protein C in the proteolytic degradation of factor Va and factor VIIIa. Decreased (antigen) levels or impaired function (activity) of protein S leads to decreased degradation of factor Va and factor VIIIa and an increased propensity to venous thrombosis. Protein S circulates in human plasma in two forms: approximately 60 percent is bound to complement component C4b β-chain while the remaining 40 percent is free. Only free protein S has activated protein C cofactor activity.

Specialty: Hematology
MeSH Codes: D018455, D020151
ICD 9 Codes: 289.81, 289.81
Source: Wikipedia

Coding Notes for D68.5 Info for medical coders on how to properly use this ICD-10 code

Inclusion Terms:
Inclusion Terms
Inclusion Terms are a list of concepts for which a specific code is used. The list of Inclusion Terms is useful for determining the correct code in some cases, but the list is not necessarily exhaustive.
Primary hypercoagulable states
Code Type-1 Excludes:
Type-1 Excludes
Type-1 Excludes mean the conditions excluded are mutually exclusive and should never be coded together. Excludes 1 means "do not code here."
Antiphospholipid syndrome - instead, use code D68.61
Lupus anticoagulant - instead, use code D68.62
Secondary activated protein C resistance - instead, use code D68.69
Secondary antiphospholipid antibody syndrome - instead, use code D68.69
Secondary lupus anticoagulant with hypercoagulable state - instead, use code D68.69
Secondary systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state - instead, use code D68.69
Systemic lupus erythematosus [SLE] inhibitor finding without diagnosis - instead, use code R76.0
Systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder - instead, use code D68.312
Thrombotic thrombocytopenic purpura - instead, use code M31.1

Coding Advice SNOMET-CT

  • Possible requirement for an external cause code

Parent Code: D68 - Other coagulation defects

** This Document Provided By ICD.Codes **
Source: http://icd.codes/icd10cm/D685