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ICD-10-CM Code D68.51
Activated protein C resistance

BILLABLE
Billable Code
Billable codes are sufficient justification for admission to an acute care hospital when used a principal diagnosis.
| ICD-10 from 2011 - 2016

D68.51 is a billable ICD code used to specify a diagnosis of activated protein C resistance. A 'billable code' is detailed enough to be used to specify a medical diagnosis.


The ICD code D685 is used to code Protein S deficiency

Protein S deficiency is a disorder associated with increased risk of venous thrombosis. Protein S, a vitamin K-dependent physiological anticoagulant, acts as a nonenzymatic cofactor to activate protein C in the proteolytic degradation of factor Va and factor VIIIa. Decreased (antigen) levels or impaired function (activity) of protein S leads to decreased degradation of factor Va and factor VIIIa and an increased propensity to venous thrombosis. Protein S circulates in human plasma in two forms: approximately 60 percent is bound to complement component C4b β-chain while the remaining 40 percent is free. Only free protein S has activated protein C cofactor activity.

Specialty: Hematology
MeSH Codes: D018455, D020151
ICD 9 Codes: 289.81, 289.81
Source: Wikipedia

Coding Notes for D68.51 Info for medical coders on how to properly use this ICD-10 code

Inclusion Terms:
Inclusion Terms
Inclusion Terms are a list of concepts for which a specific code is used. The list of Inclusion Terms is useful for determining the correct code in some cases, but the list is not necessarily exhaustive.
Factor V Leiden mutation

MS-DRG Mapping

  • DRG Group #814-816 - Reticuloendothelial and immunity disorders with MCC.
  • DRG Group #814-816 - Reticuloendothelial and immunity disorders with CC.
  • DRG Group #814-816 - Reticuloendothelial and immunity disorders without CC or MCC.

ICD-10-CM Alphabetical Index References for 'D68.51 - Activated protein C resistance'

The ICD-10-CM Alphabetical Index links the below-listed medical terms to the ICD code D68.51. Click on any term below to browse the alphabetical index.

Equivalent ICD-9 Code GENERAL EQUIVALENCE MAPPINGS (GEM)

Primary hypercoagulable state (approximate match)

This is the official approximate match mapping between ICD9 and ICD10, as provided by the General Equivalency mapping crosswalk. This means that while there is no exact mapping between this ICD10 code D68.51 and a single ICD9 code, 289.81 is an approximate match for comparison and conversion purposes.


Parent Code: D68.5 - Primary thrombophilia

** This Document Provided By ICD.Codes **
Source: http://icd.codes/icd10cm/D6851