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ICD-10-CM Code E21.0
Primary hyperparathyroidism

Billable Code
Billable codes are sufficient justification for admission to an acute care hospital when used a principal diagnosis.
| ICD-10 from 2011 - 2016

E21.0 is a billable ICD code used to specify a diagnosis of primary hyperparathyroidism. A 'billable code' is detailed enough to be used to specify a medical diagnosis.

The ICD code E210 is used to code Osteitis fibrosa cystica

Osteitis fibrosa cystica /ˌɒstiːˈaɪtᵻs faɪˈbroʊsə ˈsɪstᵻkə/, abbreviated OFC, also known as osteitis fibrosa, osteodystrophia fibrosa, and Von Recklinghausen's disease of bone (not to be confused with Von Recklinghausen's disease, neurofibromatosis type I), is a skeletal disorder caused by hyperparathyroidism, which is a surplus of parathyroid hormone from over-active parathyroid glands. This surplus stimulates the activity of osteoclasts, cells that break down bone, in a process known as osteoclastic bone resorption. The hyperparathyroidism can be triggered by a parathyroid adenoma, hereditary factors, parathyroid carcinoma, or renal osteodystrophy. Osteoclastic bone resorption releases minerals, including calcium, from the bone into the bloodstream. In addition to elevated blood calcium levels, over-activity of this process results in a loss of bone mass, a weakening of the bones as their calcified supporting structures are replaced with fibrous tissue (peritrabecular fibrosis), and the formation of cyst-like brown tumors in and around the bone. The symptoms of the disease are the consequences of both the general softening of the bones and the excess calcium in the blood, and include bone fractures, kidney stones, nausea, moth-eaten appearance in the bones, appetite loss, and weight loss.

Specialty: Endocrinology
MeSH Code: D010002
ICD 9 Code: 252.01

Osteitis fibrosa cystica of the tibia. Arrows point to the brown tumors which are typically present in bones of people with OFC.

Source: Wikipedia

Coding Notes for E21.0 Info for medical coders on how to properly use this ICD-10 code

Inclusion Terms:
Inclusion Terms
Inclusion Terms are a list of concepts for which a specific code is used. The list of Inclusion Terms is useful for determining the correct code in some cases, but the list is not necessarily exhaustive.
Hyperplasia of parathyroid
Osteitis fibrosa cystica generalisata [von Recklinghausen's disease of bone]

MS-DRG Mapping

  • DRG Group #643-645 - Endocrine disorders with MCC.
  • DRG Group #643-645 - Endocrine disorders with CC.
  • DRG Group #643-645 - Endocrine disorders without CC or MCC.

Related Concepts SNOMET-CT

  • Osteitis fibrosa cystica generalisata (disorder)


Primary hyperparathyroidism (exact match)

This is the official exact match mapping between ICD9 and ICD10, as provided by the General Equivalency mapping crosswalk. This means that in all cases where the ICD9 code 252.01 was previously used, E21.0 is the appropriate modern ICD10 code.

Parent Code: E21 - Hyperparathyroidism and other disorders of parathyroid gland

** This Document Provided By ICD.Codes **
Source: http://icd.codes/icd10cm/E210