ICD-10-CM Code E74.2
Disorders of galactose metabolism
Non-Billable CodeNon-Billable means the code is not sufficient justification for admission to an acute care hospital when used a principal diagnosis. Use a child code to capture more detail.
ICD Code E74.2 is a non-billable code. To code a diagnosis of this type, you must use one of the three child codes of E74.2 that describes the diagnosis 'disorders of galactose metabolism' in more detail.
- E74.2 Disorders of galactose metabolism NON-BILLABLE
The ICD code E742 is used to code Galactokinase deficiency
Galactokinase deficiency, also known as Galactosemia type 2 or GALK deficiency, is an autosomal recessive metabolic disorder marked by an accumulation of galactose and galactitol secondary to the decreased conversion of galactose to galactose-1-phosphate by galactokinase. The disorder is caused by mutations in the GALK1 gene, located on chromosome 17q24. Galactokinase catalyzes the first step of galactose phosphorylation in the Leloir pathway of intermediate metabolism. Galactokinase deficiency is one of the three inborn errors of metabolism that lead to hypergalactosemia. The disorder is inherited as an autosomal recessive trait. Unlike classic galactosemia, which is caused by deficiency of galactose-1-phosphate uridyltransferase, galactokinase deficiency does not present with severe manifestations in early infancy. Its major clinical symptom is the development of cataracts during the first weeks or months of life, as a result of the accumulation, in the lens, of galactitol, a product of an alternative route of galactose utilization. The development of early cataracts in homozygous affected infants is fully preventable through early diagnosis and treatment with a galactose-restricted diet. Some studies have suggested that, depending on milk consumption later in life, heterozygous carriers of galactokinase deficiency may be prone to presenile cataracts at 20–50 years of age.
|ICD 9 Code:||271.1|
ICD-10-CM Alphabetical Index References for 'E74.2 - Disorders of galactose metabolism'
The ICD-10-CM Alphabetical Index links the below-listed medical terms to the ICD code E74.2. Click on any term below to browse the alphabetical index.