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ICD-10-CM Code E88.0
Disorders of plasma-protein metabolism, not elsewhere classified

Non-Billable Code
Non-Billable means the code is not sufficient justification for admission to an acute care hospital when used a principal diagnosis. Use a child code to capture more detail.
| ICD-10 from 2011 - 2016

ICD Code E88.0 is a non-billable code. To code a diagnosis of this type, you must use one of the two child codes of E88.0 that describes the diagnosis 'disorders of plasma-protein metabolism, nec' in more detail.

The ICD code E880 is used to code Alpha 1-antitrypsin deficiency

Alpha 1-antitrypsin deficiency (α1-antitrypsin deficiency, A1AD) is a genetic disorder that causes defective production of alpha 1-antitrypsin (A1AT), leading to decreased A1AT activity in the blood and lungs, and deposition of excessive abnormal A1AT protein in liver cells. There are several forms and degrees of deficiency; the form and degree depend on whether the sufferer has one or two copies of the defective allele because it is a co-dominant trait. Severe A1AT deficiency causes panacinar emphysema or COPD in adult life in many people with the condition (especially if they are exposed to cigarette smoke). The disorder can lead to various liver diseases in a minority of children and adults, and occasionally more unusual problems. It is treated through avoidance of damaging inhalants and, in severe cases, by intravenous infusions of the A1AT protein or by transplantation of the liver or lungs. It usually produces some degree of disability and reduces life expectancy.

Specialty: Pulmonology, Medical Genetics
MeSH Code: D019896
ICD 9 Code: 273.4

Structure of Alpha 1-antitrypsin

Source: Wikipedia

Coding Notes for E88.0 Info for medical coders on how to properly use this ICD-10 code

Code Type-1 Excludes:
Type-1 Excludes
Type-1 Excludes mean the conditions excluded are mutually exclusive and should never be coded together. Excludes 1 means "do not code here."
Disorder of lipoprotein metabolism - instead, use code E78.-
Monoclonal gammopathy (of undetermined significance) - instead, use code D47.2
Polyclonal hypergammaglobulinemia - instead, use code D89.0
Waldenström macroglobulinemia - instead, use code C88.0

Related Concepts SNOMET-CT

  • Insulin resistance in diabetes (disorder)

Coding Advice SNOMET-CT

  • Possible requirement for an external cause code

Parent Code: E88 - Other and unspecified metabolic disorders

** This Document Provided By ICD.Codes **
Source: http://icd.codes/icd10cm/E880