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ICD-10-CM Code R16.1
Splenomegaly, not elsewhere classified

Billable Code
Billable codes are sufficient justification for admission to an acute care hospital when used a principal diagnosis.
| ICD-10 from 2011 - 2016

R16.1 is a billable ICD code used to specify a diagnosis of splenomegaly, not elsewhere classified. A 'billable code' is detailed enough to be used to specify a medical diagnosis.

The ICD code R161 is used to code Splenomegaly

Splenomegaly is an enlargement of the spleen. The spleen usually lies in the left upper quadrant (LUQ) of the human abdomen. Splenomegaly is one of the four cardinal signs of hypersplenism which include; some reduction in the number of circulating blood cells affecting granulocytes, erythrocytes or platelets in any combination, a compensatory proliferative response in the bone marrow, and the potential for correction of these abnormalities by splenectomy. Splenomegaly is usually associated with increased workload (such as in hemolytic anemias), which suggests that it is a response to hyperfunction. It is therefore not surprising that splenomegaly is associated with any disease process that involves abnormal red blood cells being destroyed in the spleen. Other common causes include congestion due to portal hypertension and infiltration by leukemias and lymphomas. Thus, the finding of an enlarged spleen, along with caput medusa, is an important sign of portal hypertension.

Specialty: General Surgery
MeSH Codes: D013163, D013163
ICD 9 Codes: 759.0, 789.2

CT scan showing splenomegaly in a patient with chronic lymphoid leukemia

Source: Wikipedia

Coding Notes for R16.1 Info for medical coders on how to properly use this ICD-10 code

Inclusion Terms:
Inclusion Terms
Inclusion Terms are a list of concepts for which a specific code is used. The list of Inclusion Terms is useful for determining the correct code in some cases, but the list is not necessarily exhaustive.
Splenomegaly NOS

MS-DRG Mapping

  • DRG Group #814-816 - Reticuloendothelial and immunity disorders with MCC.
  • DRG Group #814-816 - Reticuloendothelial and immunity disorders with CC.
  • DRG Group #814-816 - Reticuloendothelial and immunity disorders without CC or MCC.

Related Concepts SNOMET-CT

  • On examination - painful splenomegaly (disorder)

ICD-10-CM Alphabetical Index References for 'R16.1 - Splenomegaly, not elsewhere classified'

The ICD-10-CM Alphabetical Index links the below-listed medical terms to the ICD code R16.1. Click on any term below to browse the alphabetical index.

Splenomegaly, splenomegalia(Bengal) (cryptogenic) (idiopathic) (tropical) (R16.1)
Débove's disease(splenomegaly) (R16.1)


Splenomegaly (approximate match)

This is the official approximate match mapping between ICD9 and ICD10, as provided by the General Equivalency mapping crosswalk. This means that while there is no exact mapping between this ICD10 code R16.1 and a single ICD9 code, 789.2 is an approximate match for comparison and conversion purposes.

Parent Code: R16 - Hepatomegaly and splenomegaly, not elsewhere classified

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Source: http://icd.codes/icd10cm/R161